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Ascorbic acid



Ascorbic acid is reversibly oxidized to dehydroascorbic acid in the body. These two forms of the vitamin are believed to be important in oxidation-reduction reactions. The vitamin is involved in tyrosine metabolism, conversion of folic acid to folinic acid, carbohydrate metabolism, synthesis of lipids and proteins, iron metabolism, resistance to infections, and cellular respiration (1)

Prevention and treatment of scurvy (2)

Hyperoxaluria Cautious approach in acetylsalicylic acid hypersensitivity; G-6-PD deficiency (2)

Gastrointestinal disturbances reported with large doses Failure of conception Kidney oxalate stones. (2)

Desferrioxamine: Worsening of iron toxicity Ascorbic acid may influence the intensity and duration of action of bishydroxycoumarin. (1,2)

Ascorbic Acid Injection should be given to a pregnant woman only if clearly needed Caution should be exercised when Ascorbic Acid Injection is administered to a nursing woman. (1)

Oral Adult and child- Prophylaxis of scurvy: 25 to 75 mg daily. Treatment of scurvy: 0.5 to 1.5g/day. (2)

1.Ascorbic acid injection [Internet]. [cited 2013 October 12]. Available from: 2. National Formulary of India. 4 th ed. Government of India, Ministry of Health and Family Welfare. India: Indian Pharmacopoeia Commission; 2011